Oculomotor Control in Patients with Parkinson's Disease

There have been few studies investigating the eye movement behavior of Parkinson’s disease patients during fixation. This study objectively measured the eye movements of 36 patients with Parkinson’s disease, and 20 age matched controls. Stimuli consisted of ten standardized text passages first organized by Miller and Coleman. In addition, subjects followed a randomly displaced step jump target motion. Pendular nystagmus was found in all Parkinson’s subjects, with an average frequency of 7.44 Hz. Saccadic peak velocity and duration along the main sequence were not statistically different from controls. A slower rate of reading was also noted in the Parkinson’s group in terms of characters per minute, but with no more regressions than normal. Rate of square wave jerks was also found to be normal. This suggests that the hallmark feature of eye movements in Parkinson’s disease is a pendular nystagmus during fixation, and all saccadic activity to be normal.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Biomedical Engineering

Year dc:date.available

2009

Author dc:creator

• Gitchel, George

Contributors dc:contributor

• Paul Wetzel

• Parkinson's
• Oculomotor
• Nystagmus
• Basal Ganglia
• Biomedical Engineering and Bioengineering
• Engineering

Statement dc:rights

• © The Author

Identifier

https://scholarscompass.vcu.edu/etd/68

OAI identifier oai:identifier

oai:scholarscompass.vcu.edu:etd-1067