Experimentation and data collection involving allee effects and virulence determinations of vibrio cholerae

The proposed research focuses on the growth and potential risk associated with virulent spread of Vibrio cholerae. The thesis project is based upon a mathematical and computational simulation of pathogen dynamics that is validated via experimentation and data collection focused on the transmission and pathogenic evolution of Vibrio cholerae. While the larger scope of the project is focused around the importance of understanding Vibrio cholerae dynamics to create control and management strategies that may prevent future outbreaks, this thesis focuses on the experimentation and subsequent data collection surrounding the growth mechanisms of the bacterium under various environmental conditions. In addition, experimentation focuses on assessing virulence changes at different stages under varying virulence-inducing conditions that mimic those of a human host. This thesis discusses the methods used during experimentation, the rationale behind their selection, and the significance of the data collected in the larger scope of the project.

Grantor dc:publisher

University of Tennessee at Chattanooga

Author dc:creator

• Rojas, Erick

Contributors dc:contributor

• Harris, Bradley
• Giles, David; Danquah, Michael; Yang, Sungwoo
• College of Engineering and Computer Science

• Vibrio cholerae

Licence

• https://rightsstatements.org/page/InC/1.0/?language=en

Language dc:language

English, eng

Repository record dc:identifier

https://scholar.utc.edu/theses/620

OAI identifier oai:identifier

oai:scholar.utc.edu:theses-1778