Functional Studies of Acyl Carrier Protein and the Phosphopantetheinyl Transferase AcpT in Escherichia Coli K-12

Overexpression of AcpT was reported to suppress an E. coli K-12 mutant that has a temperature-sensitive phenotype and lipid A biosynthetic defect. I have mapped the mutation responsible for the lipid A biosynthetic defect and temperature-sensitive phenotype of this strain and have further characterized the suppression of the temperature-sensitive phenotype of strain LH530 by overexpression of AcpT.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Microbiology

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2015

Author dc:creator

• Delay, Nicholas R.

Contributors dc:contributor

• Cronan, John E., Jr

• Biology, Microbiology

Language dc:language

eng

Identifier

(MiAaPQ)AAI3269877

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/86693