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University of Illinois at Urbana-Champaign
Functional and Mechanistic Investigations of Enzymes in the Enolase Superfamily
Abstract
dc:descriptionIn this thesis, the enolase superfamily is traced phylogentically and studied in detail to ascertain which active site residues are necessary to maintain function, kinetic competence, and/or substrate specificity. Methods for understanding the details of many enzymes in the enolase superfamily are developed as well as methods for predicting the function of previously uncharacterized members of the enolase superfamily.
Degree
thesis:*- Name thesis:degree_name
- Ph.D.
- Level thesis:degree_level
- Dissertation
- Discipline thesis:degree_discipline
- Chemistry
- Grantor
- University of Illinois at Urbana-Champaign
- Year dc:date
- 2015
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Hubbard, Brian Kent
- Contributors dc:contributor
-
- Gerlt, John A.
Subjects
dc:subject × 1Rights
- Language dc:language
- eng
Identifiers
dc:identifier.*- Identifier
- (MiAaPQ)AAI9955627
- OAI identifier oai:identifier
- oai:www.ideals.illinois.edu:2142/84465