Back to search

University of Illinois at Urbana-Champaign

I. Synthetic Approaches Towards 2-Fluoroestradiol. II. Synthesis and Evaluation of Tacn-Rhenium Complexes as Estrogen Receptor Imaging Agents

Abstract

dc:description

While imaging ER levels in tumors can be done using F-18 labeled estrogens it is important to develop receptor imaging agents labeled with the widely available and less expensive technetium-99m radionuclide. We have explored the synthesis and evaluation of metal carbonyl complexes with 1,4,7-triazacyclononane. The results have suggested that these complexes are not suitable for ER imaging.

Degree

thesis:*
Name thesis:degree_name
Ph.D.
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Chemistry
Grantor
University of Illinois at Urbana-Champaign
Year dc:date
2015

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Nickels, Michael
Contributors dc:contributor
  • Katzenellenbogen, John A.

Subjects

dc:subject × 1

Rights

Language dc:language
eng

Identifiers

dc:identifier.*
Identifier
(MiAaPQ)AAI3290334
OAI identifier oai:identifier
oai:www.ideals.illinois.edu:2142/84275

Chain of custody

source
Harvested from
University of Illinois - Urbana-Champaign
Base URL
www.ideals.illinois.edu/oai-pmh
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Nickels, Michael. I. Synthetic Approaches Towards 2-Fluoroestradiol. II. Synthesis and Evaluation of Tacn-Rhenium Complexes as Estrogen Receptor Imaging Agents. Dissertation thesis, University of Illinois at Urbana-Champaign, 2015. http://hdl.handle.net/2142/84275