Selected studies in fast atom bombardment mass spectrometry

Two methods of enhancing positive ion yields in fast atom bombardment mass spectrometry (FABMS) were investigated. In one set of experiments, chemical ionization was combined with fast atom bombardment to enhance positive ion yields in FABMS. These experiments showed enhancements of over three orders of magnitude in ion currents for simple matrices. However, when extended to typical FAB systems, disproportionate enhancements in the matrix versus sample signals were observed. An additional set of experiments looked at enhancing FAB ion yields using laser irradiation. Although inadequate photon fluxes were available to photoionize the desorbed neutral species above the target, enhancements in signal intensity and fragment ion formation were observed when the laser irradiation was deposited directly into the FAB droplet on the target.

Name thesis:degree_name

Ph.D.

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry, Analytical

Grantor

University of Illinois at Urbana-Champaign

Year dc:date

2011

Author dc:creator

• Proefke, Mark L.

Contributors dc:contributor

• Rinehart, Kenneth L., Jr.

• Chemistry, Analytical

Statement dc:rights

• Copyright 1992 Proefke, Mark L.

Language dc:language

eng

Identifier

AAI9215872
(UMI)AAI9215872

OAI identifier oai:identifier

oai:www.ideals.illinois.edu:2142/23619