Growth and Respiratory Studies of Saccaromyces Cerevisiae in the Presence of Selenium

<p>The occurrence of selenium in certain soils of the United States and its detrimental effect upon livestock pastured on or fed forage from these areas has been well established. Selenium poisoning will not be reviewed here as several excellent reviews have been published (1, 2, 3). Studies on the metabolism of selenium by Sac-charomyces cerevisiae have been reported by Potter and Elvehjem (4), Lardy and Moxon (5), and Fels and Cheldelin (6, 7, 8). An attempt has been made in this thesis to repeat and enlarge on some of these studies. While this investigation may contribute information on the selenium problem, in general an attempt has been made to obtain fundamental information on the metabolism of this organism. Mammals exhibit different types of selenium poisoning, i.e. chronic and acute. This and other facts brought to light indicated that organisms are affected in different ways by varying the amount or the form of selenium administered. Possibly several enzyme systems are poisoned by the element. For this reason two different approaches to the metabolism of selenium by S. Cerevisiae have been taken (a) Growth of the organism in the presence of selenium and (b) Respiratory studies (O₂uptake) in the presence of selenium using several intermediates of glycolysis as substrates.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis - Open Access

Discipline thesis:degree_discipline

Dairy Science

Year dc:date.available

1953

Author dc:creator

• Pengra, Robert M

• Dairy Science

Statement dc:rights

• <p>In Copyright - Non-Commercial Use Permitted<br /><a href="http://rightsstatements.org/vocab/InC-NC/1.0/">http://rightsstatements.org/vocab/InC-NC/1.0/</a></p>

Language dc:language

en

Repository record dc:identifier

https://openprairie.sdstate.edu/etd/1246

OAI identifier oai:identifier

oai:openprairie.sdstate.edu:etd-2245