Evaluation of antibacterial activity of plant-food by-products and their potential application in livestock animals

Overuse and improper use of antibiotics, especially in food animals for growth promotion and disease prevention, promote the development of antibiotic resistance, which poses a severe threat to health of humans and animals. To slow the pace of antibiotic resistance and preserve the efficacy of antibiotics for both human and veterinary medicine, there is a need to develop alternatives to antibiotics. This study aims to screen and evaluate the antibacterial activity of apple peel and potato peel powder on Escherichia coli and Staphylococcus aureus, providing alternatives to antibiotics to be used in livestock animals in the future. In this study, bactericidal assay developed by Friedman et al (2002) was adopted with slight modifications to study the antibacterial activity of apple and potato peel samples. The results showed that 4 types of apple peel powder and 3 types of potato peel powder exhibited a low level of anti-E. coli activity at the concentration range from 0.03 mg/mL to 0.67 mg/mL; however, 7 types of potato peel powder showed a notable antibacterial activity on S. aureus when at or above the concentrations of 13.33 mg/mL (the resulting highest % Kill to S. aureus ranged from 68.9% to 99.3%) within three hours. The anti-S. aureus activity of potato peel was variety dependent. In conclusion, apple peel and potato peel, in particular, potato peel are promising antimicrobial agents to be used in agriculture animals in the future.

Name dc:type.qualificationname

Master of Philosophy

Level dc:type.qualificationlevel

Masters Thesis

Grantor dc:publisher.institution

Queen's University Belfast

Year dc:date.issued

2020

Author dc:creator

• Zhang, Minping

Advisors dc:contributor.advisor

• Situ, Chen
• Tunney, Michael

Language dc:language

eng

Identifier

oai:pure.qub.ac.uk/portal:studenttheses/fe67e5d0-78a4-478a-b421-358287e837f8

OAI identifier oai:identifier

oai:pure.qub.ac.uk/portal:studenttheses/fe67e5d0-78a4-478a-b421-358287e837f8