Habit Formation in a Rodent Model of Alcoholism: Genetic Susceptibility, Alcohol-Specific Effects, and Pharmacological Manipulation

Habit formation is a well-characterized process involving a shift from response-outcome as the leading driving force underlying action to a stimulus-response mechanistic process. It is hypothesized that a transition from goal-directed behavior to habitual behavior is driven by a transition of the bulk of cognitive load from neocortical toward lower neurological mechanisms. While many neurotransmitter systems have a demonstrated involvement in this process, the dopamine system is particularly implicated. Habit formation is assessed through the maintenance of extinction responding for an undesired, or devalued, outcome.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Psychological Sciences

Year

2015

Author dc:creator

• O'Tousa, David Scott

Contributors dc:contributor

• Nicholas J Grahame
• Charles Goodlett
• Stephen Boehm
• Julia Chester

• alcohol
• behavior
• dopamine
• habit
• learning
• mice

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1460

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2676