STRUCTURAL ELUCIDATION OF DEPROTONATED ANALYTES VIA TANDEM MASS SPECTROMETRY BASED ON ION-MOLECULE REACTIONS AND COLLISION-ACTIVATED DISSOCIATION

Mass Spectrometry has emerged as a powerful analytical tool for the characterization of unknown molecules. Molecular weight information and chemical formulas of the unknowns can be derived by measuring the m/z value of the ionized analyte. In addition, structural information can be obtained via tandem mass spectrometry methods such as collision-activated dissociation (CAD). However, CAD does not always guarantee unambiguously assignment of chemical structures, therefore, additional tandem mass spectrometric methods such as ion-molecule reactions were developed.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Year

2016

Author dc:creator

• Zhu, Hanyu

Contributors dc:contributor

• Hilkka I Kenttämaa
• Garth J Simpson
• Mary J Wirth
• Shelley Claridge

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1239

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2455