Phage therapy applications: Efficacy and impact on the animal intestinal microbiome

Phage therapy is a promising antibacterial intervention that has received renewed interest in recent years. In this study, the antibacterial efficacy of phage treatments was tested in different food matrices, under different conditions, as well as in both phage cocktail and single phage forms. Additionally, this study also examined phage genome sequences, bacterial phage resistance, and the impact of orally administered phages on acute immune response and gut microbiome of the host in effort to more clearly assess the safety and long-lasting efficacy of phage-based treatments.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Animal Science

Year

2015

Author dc:creator

• Hong, Yingying

Contributors dc:contributor

• Mathew G. Alan
• Paul D. Ebner
• Haley F. Oliver
• Marcos H. Rostagno

• Efficacy
• Foodborne pathogen
• Food safety
• Gut microbiome
• Phage resistance
• Phage therapy

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1115

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2331