The epidemiology of Coxiella burnetii in goats in Indiana

Coxiella burnetii is an obligate, intracellular bacterium and the etiologic agent of the zoonotic disease Q fever. Through the presence of an environmentally resilient small cell variant, C. burnetii can persist outside of a host in the face of extremes in temperature, humidity, and pressure. C. burnetii is considered to be ubiquitous in the environment and endemic in cattle, sheep and goat populations. These same species are the main reservoirs for human infection with C. burnetii. The overall goal of this project was to develop a baseline understanding of the epidemiology of C. burnetii in goats in Indiana. Specific areas addressed were: Individual and herd level prevalence of infection with C. burnetii as evaluated by serologic and molecular methods, geographic distribution of individuals and herds positive for infection with C. burnetii, and evaluation of potential risk factors for infection with C. burnetii among individual goats and herds. Six-hundred-fifty-four does representing 95 herds were included in the study sample as a whole. Six-hundred-forty-nine of the does from 94 farms were from Indiana. Based on the use of a commercial enzyme-linked immunosorbent assay (ELISA), there was a 3.8% estimated individual level and 11.2% estimated herd level seroprevalence

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Comparative Pathobiology

Year

2015

Author dc:creator

• Bauer, Amy E.

Contributors dc:contributor

• George E Moore
• Janice Kritchevsky
• Joanne B. Messick
• Roman Pogranichniy
• Hsin-Yi Weng

• Coxiella burnetii
• goats
• Indiana

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1090

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2306