Manufacturability of lab on a chip devices: tolerance analysis and requirements establishment

Decisions made during the first stages of the design process can have an impact on the cost, quality and performance of a product. Variation in assemblies, if not managed correctly during the design stage, can have a negative impact on the success of the product. This work analyzes the Daktari CD4+ Cell Counter System's capability of meeting its requirements. A Variation Simulation Model was employed to anticipate any failure modes caused by manufacturing variation and to test the robustness of the design. The design was shown to be largely successful in its ability to deliver function but unexpected failure mechanisms were found. Design considerations in the system KCs were suggested in order to minimize the effect of variation and reduce the risk of failure.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Mechanical Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2010

Author dc:creator

• Linares, Rodrigo (Rodrigo Alfonso Linares Garcia)

Advisor dc:contributor.advisor

• Brian Anthony.

• Mechanical Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/62541

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/62541