End of life resuscitation patterns : a socio-demographic study of intensive care unit patients by Sharon L. Lojun.

This study investigates the effect of age, gender, medical condition, and daily free text input on classification accuracy for resuscitation code status. Data was extracted from the MIMICII database. Natural language processing (NLP) was used to evaluate the social section of the nurses' progress notes. BoosTexter was used to predict the code-status using text, age, gender, and SAPS scoring. The relative impact of features was analyzed by feature ablation. Social text was the greatest single indicator of code status. The addition of text to medical condition features increased classification accuracy significantly (p<0.001.) N-gram frequency was analyzed. Gender differences were noted across all code-statuses, with women always more frequent (e.g. wife>husband.) Visitors and contact were more common in the less aggressive resuscitation codes. Logistic regression on medical, age, and gender features was used to determine gender bias or ageism. Evidence of bias was found; both females (OR=1.47) and patients over age 70 (OR=3.72) were more likely to be DNR. Feature ablation was also applied to the social section of physician discharge summaries, as well as to annotated features. The addition of annotated features increased classification accuracy, but the nursing social text remained the most individually predictive. The annotated features included: children; living situation; marital status; and working status. Having zero to one child; living alone or in an institution; being divorced or widow or widower; and working, working in white collar job, or being retired, were all associated with higher rates of DNR status, and lower rates of FC status. Contrarily, living with family; being married; and being unemployed, were all associated with lower rates of DNR status, and higher rates of FC status. Some of these findings were gender and/or age dependent.

Department dc:contributor.department

Harvard University--MIT Division of Health Sciences and Technology.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2010

Author dc:creator

• Lojun, Sharon L. (Sharon Lee)

Advisor dc:contributor.advisor

• Regina Barzilay.

• Harvard University--MIT Division of Health Sciences and Technology.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/57804

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/57804