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Massachusetts Institute of Technology

Decoupling market incumbency from organizational experience : a study of biotechnology's impact on the market for anti-cancer drugs

Abstract

dc:description.abstract

In studies of creative destruction, scholars agree that, within research-intensive industries, the demise of incumbents is significantly determined by their lower productivity in researching the radically new technology (Henderson, 1993). Such differences in the research competence of incumbent vs. entrant firms are explained in the literature through theories about established vs. de novo firms (e.g., Nelson and Winter, 1982). A disconnect arises because, frequently, the most competent entrants are established (experienced) firms themselves (i.e., diversifying entrants). In fact, studies where diversifying and de novo entrants are compared find in the former the same mechanisms that scholars have argued take place in incumbent firms (e.g., Mitchell and Singh, 1993; Carroll et al., 1996). With this insight in mind, I present in this dissertation a study that decouples market incumbency from organizational experience. I walk away from the current hypothesis of incompetence in research and development of a radical new technology in the case of incumbents. I instead construct a framework highlighting the competitive disadvantages (organizational inertia) and advantages (competence re-use) that apply to all established firms (incumbents and diversifying entrants) vis-a-vis de novo firms.

Degree

thesis:*
Department dc:contributor.department
Sloan School of Management.
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2006

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Sosa, M. Lourdes (María de Lourdes)
Advisor dc:contributor.advisor
  • Thomas J. Allen.

Subjects

dc:subject × 1

Rights

dc:rights
Statement dc:rights
  • M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/1721.1/36908
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/36908

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Sosa, M. Lourdes (María de Lourdes). Decoupling market incumbency from organizational experience : a study of biotechnology's impact on the market for anti-cancer drugs. Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/36908