Abstract
dc:description.abstractMerging of clinical systems and medical databases, or aggregation of information from disparate databases, frequently requires a process where vocabularies are compared and similar concepts are mapped. Using a normalization phase followed by a novel alignment stage inspired by DNA sequence alignment methods, automated lexical mapping can map terms from various databases to standard vocabularies such as UMLS (Unified Medical Language System) and SNOMED (the Systematized Nomenclature of Medicine). This automated lexical mapping was evaluated using a real-world database of consultation letters from Children's Hospital Boston. The first phase involved extracting the reason for referral from the consultation letters. The reasons for referral were then mapped to SNOMED. The alignment algorithm was able to map 72% of equivalent concepts through lexical mapping alone. Lexical mapping can facilitate the integration of data from diverse sources and decrease the time and cost required for manual mapping and integration of clinical systems and medical databases.
Degree
thesis:*- Department dc:contributor.department
- Harvard University--MIT Division of Health Sciences and Technology.
- Grantor dc:publisher
- Massachusetts Institute of Technology
- Year dc:date.issued
- 2005
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Sun, Jennifer Y. (Jennifer Yiling)
- Advisor dc:contributor.advisor
-
- Isaac S. Kohane.
Subjects
dc:subject × 1Rights
dc:rights- Statement dc:rights
-
- M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
- Licence dc:rights.uri
- Language dc:language.iso
- eng
Identifiers
dc:identifier.*- Handle dc:identifier.uri
- http://hdl.handle.net/1721.1/33083
- OAI identifier oai:identifier
- oai:dspace.mit.edu:1721.1/33083