Structural studies of bacterial multicomponent monooxygenases : insights into substrate specificity, diiron center tuning and component interactions

(cont.) α-subunit cavities. The presence of 6-bromohexan-l-ol induces one of the active site helices to adopt a [pi] conformation. Together, these findings suggest modes by which molecules may move through the MMOH cavities and how both substrates and MMOB may influence the structure of the active site pocket.

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Chemistry

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2004

Author dc:creator

• Sazinsky, Matthew H. (Matthew Howard), 1976-

Advisor dc:contributor.advisor

• Stephen J. Lippard.

• Chemistry.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/28702

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/28702