Microfluidic and electronic detection of protein biomarkers

Proteins are essential components of our bodies and play critical roles in biological processes. Quantifying protein levels can help characterize these biological processes and detect malfunctions. Thus, protein testing is widely utilized in clinical diagnostics. The current workflow for protein testing involves the processing of patient samples that are collected at healthcare facilities. These samples are sent to centralized laboratories and analyzed using sophisticated instruments. As a result, it can take days to deliver results. However, to manage acute conditions such as sepsis, rapid results are desired to ensure timely diagnosis and treatment. In contrast, point-of-care testing has shown great promise for rapid results through the use of miniaturized and inexpensive devices in non-laboratory settings.

Name thesis:degree_name

Doctoral

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Mechanical Engineering

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2020

Author dc:creator

• Wu, Dan,Ph.D.Massachusetts Institute of Technology.

Advisor dc:contributor.advisor

• Joel Voldman.

• Mechanical Engineering.

Statement dc:rights

• MIT theses may be protected by copyright. Please reuse MIT thesis content according to the MIT Libraries Permissions Policy, which is available through the URL provided.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/1721.1/127733

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/127733