Whispering photons : on-chip biophotonic integrated circuits for point-of-care diagnostics

The pressure of increasing service demands and improving turnaround times of results in healthcare industry require the development of more rapid, point-of-care and personalized diagnostic tools. Light is ubiquitous in biology and offers various elegant solutions for diagnostic, therapies and theranostic applications. At present, there is not a single biomedical application where optical components are not applied. If we can come up with a framework that can miniaturize these optical components on a chip, it can offer various advantages in terms of scalability, portability, cost and improved performance for real-time monitoring and bedside treatment. On these lines, we propose bio-photonic integrated circuits (Bio-PICs) for point-of-care diagnostics. These circuits rely on moving photons in photonic waveguides (similar to electrons in your electronic chips) to provide on-chip sensing solution. Specifically, we present Bio-PICs for aerosol spectroscopy, blood coagulometry, and TB breath analyzer test.

Name thesis:degree_name

Master

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Mechanical Engineering

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2018

Author dc:creator

• Singh, Robin,Ph. D.Massachusetts Institute of Technology.

Advisor dc:contributor.advisor

• Brian W. Anthony and Anuradha Murthy Agarwal.

• Mechanical Engineering.

Statement dc:rights

• MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/1721.1/122425

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/122425