Insulin and Glucagon Responses to Dietary Protein in Diabetic and Nondiabetic Men

<p>Five men with non-insulin-dependent diabetes mellitus and fourteen nondiabetic men, were given test meals with soy protein, casein or additional carbohydrate in place of protein. Blood levels of insulin, glucagon, glucose and lipids were measured at fasting, one-half hour and two hours postprandial. To all meals, the nondiabetic subjects responded with a quick rise of the insulin level which decreased at two hours. In contrast, the diabetics showed a significantly lower insulin response at one-half hour (p < 0.05), but a tendency to higher levels at two hours. The same pattern was observed in the insulin to glucagon ratio. No significant difference between the meals was found in regard to insulin or glucagon responses, suggests that a sustained, although delayed postprandial insulin response, may be a precursor to the higher cholesterol and increased risk for cardiovascular disease among diabetics.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Nutrition

Year

1987

Author dc:creator

• Blomstedt, Monica L.

Contributors dc:contributor

• Albert Sanchez
• Richard W. Hubbard
• U. D. Register
• Gerald Shavlik

• Amino Acids, Peptides, and Proteins
• Cardiovascular Diseases
• Endocrinology, Diabetes, and Metabolism
• Hormones, Hormone Substitutes, and Hormone Antagonists
• Laboratory and Basic Science Research
• Nutrition
• Diabetes Mellitus; Cardiovascular Diseases; Insulin

Statement dc:rights

• This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Language dc:language

English

Repository record dc:identifier

https://scholarsrepository.llu.edu/etd/1506

OAI identifier oai:identifier

oai:scholarsrepository.llu.edu:etd-2282