ΡΙΤΟΔΡΙΝΗ ΚΑΙ ΕΝΔΟΚΥΤΤΩΣΗ (ΠΕΙΡΑΜΑΤΙΚΗ ΕΡΓΑΣΙΑ IN VIVO)

THE EFFECT OF RITODRINE ON THE PHAGOCYTIC ACTIVITY OF THE MONONUCLEAR PHAGOCYTES (M.P.S.) WAS STUDIED IN VIVO. THE CLEARANCE OF A CERTAIN QUANTITY OF CARBONPARTICLES (250A) FROM THE CIRCULATION WAS TAKEN AS AN INDICATOR OF THE PHAGOCYTIC ACTIVITY OF MPS ACCORDING TO THE METHOD PROPOSED BY HALPERN AND HIS COLABORATORS. FOR THE EXPERIMENTS ISOGENIC SWISS ALBINO A MICE WERE USED. THE ANIMALS WERE DISTRIBUTED INTO EIGHT GROUPS AS FOLLOWS: GROUP (A) INCLUDED 19 ANIMALS THAT SERVED AS CONTROLS. GROUP (B) INCLUDED 8 ANIMALS TO WHICH 31,25 MG RITODRINE WAS INJECTED INTRAPERITONEALLY (I.P.). GROUP (C) INCLUDED 8 ANIMALS TO WHICH 62,5 MG OF RITODRINE WAS INJECTED (I.P.). GROUP (D) INCLUDED 8 ANIMALS TO WHICH 125 MG OF RITODRINE WAS INJECTED (I.P.). GROUP (E) INCLUDED 8 ANIMALS TO WHICH 250 MG OF RITODRINE WAS INJECTED (I.P.). GROUP (F) INCLUDED 8 ANIMALSTO WHICH 375 MG OF RITODRINE WAS INJECTED (I.P.). GROUP (G) INCLUDED 12 ANIMALS TO WHICH 500 MG OF RITODRINE WAS INJECTED (I.P.). GROUP (H) INCLUDED 13 ANIMALS TO WHICH 500 MG OF RITODRINE WAS INJECTED INTRAMUSCULARLY. RITODRINE WASINJECTED THREE HOURS BEFORE THE BEGINNING OF THE EXPERIMENTS. FROM THE RESULTS OF THIS STUDY, WE COME TO THE CONCLUSION THAT THE INTRAPERITONEALLY INJECTEDRITODRINE, CAUSES AN INCREASE OF THE OVERALL PHAGOCYTIC ACTIVITY OF THE MACROPHAGES, IN VIVO, AND THIS INCREASE, WHICH, IS DOSE DEPENDED, EXPRESSES THE INCREASE OF PHAGOCITIC ACTIVITY PER SE AS WELL AS THE INCREASE OF THE NUMBER OF MACROPHAGES OF LIVER AND SPLEEN.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1985

Author dc:creator

• Μάμας, Λεωνίδας

• Ενδοκύττωση
• Ριτοδρίνη
• PHAGOCYTIC ACTIVITY
• RITODRINE
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0411

OAI identifier oai:identifier

oai:10442/0411