ΜΕΤΑΤΡΙΧΟΕΙΔΗ ΦΛΕΒΙΔΙΑ: ΜΕΤΑΒΟΛΕΣ ΕΝΔΟΘΗΛΙΑΚΩΝ ΚΥΤΤΑΡΩΝ ΑΠΟ ΟΙΣΤΡΟΓΟΝΑ ΚΑΙ ΑΝΤΙΟΙΣΤΡΟΓΟΝΑ ΣΕ ΠΟΝΤΙΚΟΥΣ

THE ALTERATIONS OF LYMPH NODE POST-CAPILLARY VENULES (PCV) RESULTED FROM TREATMENT OF MALE MICE WITH ESTROGENS AND ANTIESTROGENS WERE STUDIED, LIGHT - AND ELECTRON MICROSCOPICALLY. ESTROGENS RESULT IN A SIGNIFICANT INCREASE OF THE HEIGHT OF ENDOTHELIAL CELLS IN PCV ACCOMPANIED BY AN AUGMENTATION OF GOLGI APPARATUS. ANTI-ESTROGENS INDEPENDENT OF DOSES EVOKE SOMEWHAT SMALLER THAN ESTROGENSINCREASE OF PCV ENDOTHELIAL CELL HEIGHT. FURTHER TREATMENT WITH ESTROGENS EVOKES AN INSIGNIFICANT ADDITIONAL HEIGHT INCREASE. ANTI- ESTROGENS RESULT IN PROLIFERATION AND AUGMENTATION OF MITOCHONDRIA, FREE RIBOSOMES AND ROUGH ENDOPLASMIC RETICULUM. ADDITION OF ESTROGENS INCREASES THE PROFILES OF GOLGI APPARATUSLESS THAN WHEN THEY ARE GIVEN ALONE. ESTROGENS AND LARGE DOSES OF ANTIESTROGENS DECREASE SIGNIFICANTLY THE THYMUS WEIGHT. SMALL DOSES OF ANTIESTROGENS ACTION ON THYMUS (AND T-LYMPHOCYTES) CANNOT BE EXPLAINED INDIRECTLY BY BLOCKING RECEPTORS IN HYPOPHYSIS. A DIRECT ACTION OF ANTI-ESTROGENS ON THE THYMOUS MUST BE CONSIDERED. THE ABOVE FINDING ARE NEW AND ADDITIONAL PROOF THAT ESTROGENS AND ANTI- ESTROGENS, AS WELL, INFLUENCE THE STRUCTURAL STATUS OF PCV ENDOTHELIAL CELL DIRECTLY AND NOT ALTERING THE RATE OF CIRCULATING T- LYMPHOCYTES THROUGHTHE PCV WALL.

Grantor dc:publisher

University of Ioannina

Year dc:date

1986

Author dc:creator

• Στεφανάκη-Νίκου, Στυλιανή

• ANTI-ESTROGENS
• Estrogens
• POSTCAPILLARY VENULES (PCV)
• Thymus
• Αντιοιστρογόνα
• Θυμός
• ΜΕΤΑΤΡΙΧΟΕΙΔΗ ΦΛΕΒΙΔΙΑ (ΜΤΦ)
• Οιστρογόνα
• Παθολογική ανατομία
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0260

OAI identifier oai:identifier

oai:10442/0260