Multi-omic health profiling in the critically endangered black rhinoceros (Diceros bicornis)

Black rhinoceros (Diceros bicornis; “black rhinos”) experience extinction threats in-situ because of poaching pressures. Simultaneously, the ex-situ population, which serves as a genetic reservoir against impending extinction threats, experiences its own threats to survival related to several disease syndromes not typically observed among their wild counterparts. The etiologies of these disease syndromes remain under studied. Further, the physiological mechanisms that underpin these syndromes are not fully understood. In this dissertation, we employed the use of multiomic profiling: metabolomic, immunoproteomic, metagenomic, and dietary metataxonomic datasets to identify the physiological pathways that appear perturbed in animals with disease phenotypes. We hope these findings will improve the overall health and wellbeing of black rhinos in managed care.

Author

• Corder, Molly Loy

• Bioinformatics
• Black rhinoceros
• Conservation medicine
• Diceros bicornis
• Multi-omic
• Omics

Identifier

hdl:1920/14511

OAI identifier oai:identifier

oai:MARS:1920/14511