In-Vitro and In-Silico Investigations of Alternative Surgical Techniques for Single Ventricular Disease

<p>Single ventricle (SV) anomalies account for one-fourth of all cases of congenital Heart disease. The conventional second and third stage i.e. Comprehensive stage II and Fontan procedure of the existing three-staged surgical approach serving as a palliative treatment for this anomaly, entails multiple complications and achieves a survival rate of 50%. Hence, to reduce the morbidity and mortality rate associated with the second and third stages of the existing palliative procedure, the novel alternative techniques called “Hybrid Comprehensive Stage II” (HCSII), and a “Self-powered Fontan circulation” have been proposed. The goal of this research is to conduct in-vitro investigations to validate computational and clinical findings on these proposed novel surgical techniques. The research involves the development of a benchtop study of HCSII and self-powered Fontan circulation.</p>

Name thesis:degree_name

Doctor of Philosophy in Mechanical Engineering

Level thesis:degree_level

Dissertation - Open Access

Discipline thesis:degree_discipline

Mechanical Engineering

Year

2021

Author dc:creator

• Das, Arka

• heart surgery
• ventricular disease
• alternative
• in-vitro
• in-silico
• Cardiovascular Diseases
• Mechanical Engineering

Repository record dc:identifier

https://commons.erau.edu/edt/607

OAI identifier oai:identifier

oai:commons.erau.edu:edt-1618