Studies on the Beckmann Rearrangement of 3beta-Acetoxycholest-5-En-7-One Oxime: Synthesis Of 3beta-Acetoxy-7a-AZA-B-Homocholest-5-En-7-One

The synthetic modification of naturally occuring steroids has yielded an increasing number of biologically active and therapeutic agents. Modifications of known steroids (androgens, estrogens, progestogens, corticoids, and mineral corticoids) have produced compounds possessing new biological properties, and increased therapeutic value. | Among the modified steroids of interest are the nitrogen-containing azasteroids. The purpose of this investigation was to synthesize one such azasteroid, 3beta-acetoxy-7a-aza-B-homocholest-S-en-7-one via the Beckmann rearrangement of 3beta-acetoxycho-lest-5-en-7-one oxime.

Grantor dc:publisher

Creighton University

Year dc:date.issued

1964

Author dc:creator

• Hahn, Kwang J.

Advisor dc:contributor.advisor

• Takemura, Kaz H.

Statement dc:rights

• A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/10504/109575

OAI identifier oai:identifier

oai:cdr.creighton.edu:10504/109575