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Department of Molecular and Cell Biology

Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites

Abstract

dc:description.abstract

This thesis exposes previously ignored evolutionary characteristics of the synonymous sites of virus nucleotide sequences and contributes new findings to the understanding of the evolution of HIV-1 in relation to the human immune response.

Degree

thesis:*
Grantor dc:publisher.institution
Department of Molecular and Cell Biology
Year dc:date.issued
2009

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Ngandu, Nobubelo Kwanele
Advisor dc:contributor.advisor
  • Seoighe, Cathal

Rights

Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/11427/3072
OAI identifier oai:identifier
oai:open.uct.ac.za:11427/3072

Chain of custody

source
Harvested from
University of Cape Town
Base URL
open.uct.ac.za/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
related terms
citation

Ngandu, Nobubelo Kwanele. Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites. Department of Molecular and Cell Biology, 2009. http://hdl.handle.net/11427/3072