Phenotypic and functional characterisation of cervical and peripheral HIV-1 specific T cell responses

Distinct HIV variants occur at the genital mucosa compared to in blood, which may similarly result in differences in HIV T cell responses. There have been no studies of the maturational status of HIV-specific T cells present at the female genital mucosa. This study aimed to characterise HIV-specific cervical immune responses and to determine if compartmentalized immune responses occur in chronic HIV infection by comparing the characteristics of T cells at the cervical mucosa to those in blood.

Grantor dc:publisher.institution

Division of Medical Microbiology

Year dc:date.issued

2007

Author dc:creator

• Liebenberg, Lenine Julie

Advisors dc:contributor.advisor

• Passmore, Jo-Ann
• Burgers, Wendy

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/11427/2712

OAI identifier oai:identifier

oai:open.uct.ac.za:11427/2712