Abstract
dc:descriptionThe development of new and efficient catalysts is of utterly importance for the improvement of existing reactions and the discovery of new catalytic reactions. On the one hand this PhD thesis deals with the synthesis of novel, enantiopure diphosphines and phosphine-olefin-complexes bearing a cyrhetrene backbone, which catalyze various reactions, e.g. the Hayashi-Miyaura-reaction and the hydrogenation of arylenamides, with high selectivities. On the other hand the first asymmetric intermolecular hydroacylation of olefins with salicylaldehydes was developed. A variety of rhodium(I) complexes were examined by in situ preparation from the corresponding catalyst precursors and phosphorous-containing monodentate and bidentate ligands. Application of bidentate ligands such as members of the Taniaphos or the Walphos family furnished the exo-diastereomer predominantly and with up to 82% ee. In contrast, the use of monodentate ligands such as the phosphoramidite MonoPhos™ led diastereoselectively to the endo-diastereomer with up to 54% ee. Initial experiments with bidentate phosphoramidite-phosphite derivatives of hydroxyproline provided promising results, giving the exo-diastereomer predominantly with up to 84% ee.
Degree
thesis:*- Grantor dc:publisher
- Mainz
- Year dc:date
- 2007
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Stemmler, René T.
- Contributors dc:contributor
-
- Bolm, Carsten
Subjects
dc:subject × 14Rights
dc:rights- Statement dc:rights
-
- info:eu-repo/semantics/openAccess
- Language dc:language
- ger
Identifiers
dc:identifier.*- OAI identifier oai:identifier
- oai:publications.rwth-aachen.de:62367