Kenngrößenorientierte Beurteilung von Rotationsblutpumpen diagonaler Bauart mittels numerischer Strömungssimulation

The aim of this work was to analyse the flow phenomena within the implantable rotary blood pump “MikroDiagonalPump” (MDP) by means of Computational Fluid Dynamics (CFD). In the first part, a method has been developed to evaluate different pump geometries and impeller variations in a standardised and efficient way. The evaluation was focussed on three impeller designs which feature different blade designs and/or wash-up concepts at the impeller rear side. Also, the gaps and the inlet and outlet areas of the pump were specified for the evaluation. Based on the system requirements, hydraulic and hemodynamic key characteristics have been defined to ensure a systematic comparison. These characteristics were automatically calculated during the post-processing. The second part of this work was focussed on the numerical estimation of the flow induced hemolysis for rotary blood pumps. Therefore, a new approach calculating the “accumulated” blood damage in rotary blood pumps was chosen to develop a semi-empiric model. In most published models, blood damage is locally calculated and subsequently accumulated along flow paths. In contrast, a power law function was defined depending on the key characteristics for different pump operating conditions determined in the first part. The unknown constants of this function were determined based on in-vitro hemolysis data for different operating conditions of MDP by means of regression analysis. Finally, the model was successfully validated based on the in-vitro hemolysis data of the three different impeller designs at the physiological operating point which is a major advantage of this model. Furthermore, this new model features two specialities regarding the calculating procedure. On one hand, averaged values for the key characteristics on each operating point are applied (in contrast to local blood damage calculation). On the other hand, the direct impact of the stress threshold and the indirect impact of the pressure head were taken into the account.

Grantor dc:publisher

Publikationsserver der RWTH Aachen University

Year dc:date

2006

Author dc:creator

• Arvand, Arash

Contributors dc:contributor

• Rau, Günter

• info:eu-repo/classification/ddc/620
• Numerische Strömungssimulation
• Blutpumpe
• Hämolyse
• Modellierung
• In vitro
• Ingenieurwissenschaften
• strömungsinduzierte Hämolyse
• Hämolysemodell
• CFD
• rotationsblutpumpe
• MikroDiagonalPumpe MDP
• flow induced blood damage
• hemolysis model
• rotary blood pump
• MikroDiagonalPump MDP

Statement dc:rights

• info:eu-repo/semantics/openAccess

Language dc:language

ger

Identifier

https://publications.rwth-aachen.de/search?p=id:%22RWTH-CONV-123420%22

OAI identifier oai:identifier

oai:publications.rwth-aachen.de:61796